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Anesthesia for Egg Retrieval: What to Expect at the Fertility Clinic

How sedation for egg retrieval works, how to prepare, what you will feel, and how soon you can go home.

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Egg (oocyte) retrieval is a short procedure, typically lasting 15 to 30 minutes, in which eggs are collected from the ovaries with a fine needle guided by ultrasound. Because it can be uncomfortable, it is usually performed with intravenous sedation administered by an anesthesia professional.

What kind of anesthesia is used?

Most retrievals use intravenous sedation — often with propofol, sometimes combined with a short-acting pain medication. You breathe on your own, and most patients remember little or nothing of the procedure. A 2018 Cochrane review of pain relief for oocyte retrieval found that no single method was clearly superior, and that sedation combined with pain relief generally improved comfort compared with less intensive approaches.1

Sedation exists on a continuum, from minimal to deep, and the ASA defines each level by how responsive you are and how well you breathe on your own.2 Your anesthesiologist monitors you continuously and adjusts the depth throughout.

How to prepare

Follow the fasting instructions you are given exactly; they exist to reduce the risk of stomach contents entering the lungs under sedation. Share a complete list of medications and supplements, including your fertility medications. Arrange for an adult to take you home, because you should not drive after sedation.

Recovery

You will rest in a recovery area until you are awake and stable. Mild cramping, bloating and spotting are common afterwards. Under the ASA statement on office-based anesthesia, discharge is a physician responsibility, and you should leave with written instructions on whom to call.3 Contact your clinic promptly for severe abdominal pain, fever, heavy bleeding, shortness of breath or marked swelling.

Dr. Seitz provides anesthesia at fertility clinics.

Sources

  1. Kwan I, Wang R, Pearce E, Bhattacharya S. Pain relief for women undergoing oocyte retrieval for assisted reproduction. Cochrane Database Syst Rev. 2018;5(5):CD004829.
  2. American Society of Anesthesiologists. Statement on Continuum of Depth of Sedation: Definition of General Anesthesia and Levels of Sedation/Analgesia. Last amended October 23, 2019.
  3. American Society of Anesthesiologists. Statement on Office-Based Anesthesia. Original approval October 13, 1999; last amended October 23, 2024.
Portrait of Dr. John Seitz, MD

Dr. John Seitz, MD

Board-certified anesthesiologist

This article is for general educational purposes and is not a substitute for personalized medical advice. Always consult your physician for guidance specific to your health.

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